Video tutorials
Navigating the AsthmaMap
Commenting
Exploring drug targets
Visualising data
Navigating the AsthmaMap
Video duration: 4 min
This tutorial describes how to navigate the AsthmaMap resource and use the search functionality in MINERVA.
Specific maps of the Molecular Relations and Biochemical Mechanisms layers can be accessed via the provided “Open in MINERVA” links.
As described in the video, to access submaps in MINERVA please use the buttons on the left side of the map and then click on the corresponding link in the left-side menu, or, alternatively, use the SUBMAPS tab in MINERVA.
Commenting
Video duration: 4 min
This tutorial describes how comments can be added directly to the map.
The Eicosanoid Production Map used for this tutorials is available at https://asthma.uni.lu/minerva/index.xhtml?id=aa.
The pathway of COX1/2 acetylation by aspirin: https://metabolismregulation.org/aspirin.
Exploring drug targets
Video duration: 3 min
This tutorial describes how to use the MINERVA drug search funcitonality and explore drug targets via online queries to DrugBank and CHEMBL.
Visualising data
Video duration: 5 min
This tutorial describes how to use the MINERVA overlay functionality to visualise data, including multi-omics data.
The multi-omics data and analysis presented in this video are reported as a conference abstract: De Meulder et al., 2015, Eur Respir J. DOI: 10.1183/13993003.congress-2015.PA4889; and the analytics methodology is published in De Meulder et al., 2018, BMC Syst Biol. DOI: 10.1186/s12918-018-0556-z.
Links to the individual datasets are provided below:
- Clinical data and U-BIOPRED adult cohort: Shaw et al., 2015, Eur Respir J. PMID: 26357963. DOI: 10.1183/13993003.00779-2015.
- Peripheral blood transcriptomics: Bigler et al., 2017, Am J Respir Crit Care Med. PMID: 27925796. DOI: 10.1164/rccm.201604-0866OC.
- Urine eicosanoids: Kolmert et al., 2020, Am J Respir Crit Care Med. PMID: 32667261. DOI: 10.1164/rccm.201909-1869OC.