The AsthmaMap project is led by the European Institute for Systems Biology and Medicine, Lyon, France. The effort was initiated as a part of the IMI U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes) data analysis and integration platform and then continued within IMI eTRIKS project (European Translational Information and Knowledge Management Services).

An important part of the AsthmaMap development is the involvement of top experts in the field of asthma, allergic diseases and lung diseases. This way we make sure we are building a trusted reference resource and the results of this work go towards practical applications in clinics.

AsthmaMap is being developed in close collaboration with the LCSB Parkinson’s disease map team. MINERVA platform is employed for online visualisation.

The AsthmaMap project progresses in alliance with other efforts of the Disease Maps Community and communicates with other groups for exchanging experience and best practices.

How to cite

Mazein A, Ivanova O, Balaur I, Ostaszewski M, Berzhitskaya V, Serebriyskaya T, Ligon T, Hasenauer J, De Meulder B, Overall RW, Roy L, Knowles RG, Wheelock CE, Dahlen SE, Chung KF, Adcock IM, Roberts G, Djukanovic R, Pellet J, Gawron P, Balling R, Maitland-van der Zee AH, Schneider R, Sterk PJ, Auffray C; U-BIOPRED Study Group and the eTRIKS Consortium. AsthmaMap: an interactive knowledge repository for mechanisms of asthma. J Allergy Clin Immunol. 2020 Dec 9:S0091-6749(20)31707-3. doi: 10.1016/j.jaci.2020.11.032. PMID: 33309742.

Mazein A, Knowles RG, Adcock I, Chung KF, Wheelock CE, Maitland-van der Zee AH, Sterk PJ, Auffray C; AsthmaMap Project Team. AsthmaMap: An expert-driven computational representation of disease mechanisms. Clin Exp Allergy. 2018 Aug;48(8):916-918. doi: 10.1111/cea.13211. PMID: 30133857.


We actively support the strengthening tendency to large-scale participative open-community projects for approaching complex diseases and welcome collaboration on the topic of high-quality reconstruction of asthma mechanisms, modelling, hypothesis generation and validation.


To contribute and discuss the project please use this email address: asthma-map@googlegroups.com

AsthmaMap Project Coordinators:
Alexander Mazein a.mazein@gmail.com
Charles Auffray cauffray@eisbm.org


All the files are available for downloading via the Downloads page.

Press release

New “AsthmaMap” could redefine disease and personalize treatment for patients, 12th March 2016, European Lung Foundation. Read…


Funded in part by the Innovative Medicines Initiative (IMI) funded by the European Union and the European Federation of Pharmaceutical Industry Associations through U-BIOPRED (Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes, n°115010) and eTRIKS (European Translational Information and Knowledge Management Services, IMI n°115446), the French National Center for Scientific Research (CNRS), the European Institute for Systems Biology and Medicine and the Luxembourg Center for Systems Biomedicine.