Glomerular filtration rate (GFR) is a crucial marker of renal (kidney) health.
Estimated GFR (eGFR) is a mathematical construct based on the age, sex, ethnicity, and serum creatinine level of a person. This is typically determined through the laboratory's analysis of the blood sample and reported together with the serum creatinine result.
- “Normal” GFR is typically greater than 90 ml/min/1.73 m2, indicating normal kidney function.
- In the initial stages of kidney disease, however, the eGFR could be normal despite the presence of some signs of kidney damage, such as protein in the urine.
- According to the National Kidney Foundation, the normal range is between 90 and 120 mL/min/1.73 m2.
What is GFR?
Glomerular filtration rate (GFR) is a blood test that measures how well the kidneys are functioning. Glomeruli are microscopic filters found in the kidneys. These filters aid in the removal of waste and extra fluid from the blood. Blood flow through these filters is measured by a GFR test. A GFR can be directly assessed, but it is a challenging procedure that needs skilled experts.
The most common method to express GFR is the estimated GFR test or eGFR.
- To provide an estimate, your practitioner will utilize a process called the GFR calculator.
- The GFR calculator is a particular kind of mathematical formula that determines the rate of filtration of blood by the kidneys.
- This is accomplished by using your personal information, such as age, gender, height, weight, and ethnicity.
- The findings of the blood test analyze the amount of creatinine, a waste product that is filtered by the kidneys.
- Medical professionals gauge eGFR in milliliters of blood that has been cleansed per minute per unit of body surface (mL/min/1.73m2).
What is the purpose of the eGFR test?
The early-stage renal disease normally has no symptoms. Estimated glomerular filtration rate (eGFR) testing could be advised by your doctor if you are at increased risk of developing renal disease.
Risk elements for chronic kidney disease (CKD) include:
- Diabetes
- Elevated blood pressure
- Excess weight
- Hereditary kidney disease
CKD in its later stages does have symptoms. If you have any of the following signs, you may require an eGFR test:
What might affect your test result?
Your test outcome may not be as precise if you fall under any of the following categories:
- Severely undernourished, underweight, or have an illness that causes muscle wasting
- Significantly overweight
- Possess a neuromuscular condition
- Take any medications, such as chemotherapies or renal medications
- Consume lots of meat
- Take creatine supplements
- Pregnant
- Possess above-average muscle mass, such as a bodybuilder
QUESTION
See AnswerWhat do your test results mean?
Your age, gender, medical history, and other factors may affect the test findings. Depending on the lab utilized, the results of your test may change. Consult your doctor to learn the implications of your test results for you.
Kidney disease has five stages. Based on the degree of kidney damage indicated by your estimated glomerular filtration rate (eGFR), your healthcare professional defines your stage.
- Stage I (eGFR of 90 mL/min/1.73m2 or higher): Indicates possible kidney damage (protein in the urine) with normal renal function.
- Stage II (eGFR between 60 and 89 mL/min/1.73m2): Indicates renal injury combined with a slight reduction of kidney function.
- Stage III (eGFR between 30 and 59 mL/min/1.73m2): Minimal to moderate renal functional loss.
- Stage IV (eGFR between 15 and 29 mL/min/1.73m2): Severe impairment of kidney function.
- Stage V (eGFR below 15 mL/min/1.73m2): Indicates kidney failure. It is potentially fatal at this level. You will require a kidney transplant or dialysis (a procedure that filters out wastes from your blood).
What are the risks associated with this test?
The risk of having your blood taken is negligible. The dimensions of veins and arteries differ among people and from one side of the body to the other. It could be more challenging to take a blood sample from some people than from others.
The following are a few minor additional dangers that may be present when withdrawing a blood sample:
- Bleeding excessively
- Fainting or experiencing dizziness
- Several punctures to find veins
- Hematoma (blood accumulating under the skin)
- Infection (whenever the skin is broken there can be a minor possibility for skin infection)
Health News
- Unhealthy Microbiome May Raise Death Risk After Organ Transplant
- Raw Milk Exposure a Real Bird Flu Risk for Humans, but Fast Spread Unlikely
- Second Recipient of Genetically Modified Pig Kidney Has Died
- Doctors Perform Larynx Transplant in Cancer Patient
- Scientists Develop High-Tech 'Air Mask' to Ward Off Viruses
- More Health News »
Estimated Glomerular Filtration Rate (eGFR). https://www.kidney.org/atoz/content/gfr Kidney Failure Risk Factor: Estimated Glomerular Filtration Rate (eGFR). https://www.kidney.org/content/kidney-failure-risk-factor-estimated-glomerular-filtration-rate-egfr
What Is a Glomerular Filtration Rate (GFR)? https://www.webmd.com/a-to-z-guides/glomerular-filtration-rate
Glomerular filtration rate. https://www.ucsfhealth.org/medical-tests/glomerular-filtration-rate
Glomerular Filtration Rate. https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=167&contentid=glomerular_filtration_rate
Top What Does It Mean If eGFR Is High Related Articles
Can Drinking Water Stop Kidney Failure?
While drinking more water can help boost kidney function, there is no evidence that suggests that it can prevent the progress of kidney failure.How Can I Check My Kidneys at Home?
Albumin home test kits and smartphone-enabled home urinalysis devices are available to check your kidney function at home.How Long Can You Live With a Kidney Transplant?
According to studies, 1-year survival rates for kidney transplants range from 93%-98%, and 5-year survival rates range from 83%-92%.How Long Do Kidney Transplants Last?
The duration for which a transplanted kidney lasts may vary from person to person. On average, kidney transplants may last for around 10-12 years.Kidney Disease Quiz
Kidney disease is common. Take this kidney disease quiz to test your knowledge and learn the symptoms, causes and types of kidney disease and what foods to eat and avoid!Kidney Failure
Kidney failure can occur from an acute event or a chronic condition or disease. Prerenal kidney failure is caused by blood loss, dehydration, or medication. Some of the renal causes of kidney failure include sepsis, medications, rhabdomyolysis, multiple myeloma, and acute glomerulonephritis. Post-renal causes of kidney failure include bladder obstruction, prostate problems, tumors, or kidney stones. Treatment options included diet, medications, or dialysis.Kidney Health: Warning Signs of Kidney Problems
Your kidneys are your body's clearinghouse for toxins. Learn what swollen feet, muscle cramps, and other warning signs may signal about your kidneys' health.Kidney Stone Slideshow
What causes kidney stones? Where is kidney stone pain located on your body? Learn the symptoms and signs of kidney stone pain. Explore kidney stone treatment and how to prevent kidney stones.Kidneys Picture
The kidneys are a pair of organs located in the back of the abdomen. See a picture of the Kidneys and learn more about the health topic.How Long Can a Nephrostomy Tube Remain in the Kidney?
A nephrostomy tube can remain in the kidney as long as the obstruction in your urinary tract does not get relieved. It may need to stay in for a short time such as till a stone passes naturally. It may be needed for only two to three days, or it may need to stay in for a much longer period to allow a more permanent solution for the blockage to be organized.Surprising Things That Can Hurt Your Kidneys
Your kidneys do a lot for you. But are you helping or hurting them? Click through the WebMD quiz to find out how you might be damaging your kidneys without even knowing it.Ways to Keep Your Kidneys Healthy
You might know that more than a drink or two a day is bad for your health. But in some cases, any alcohol at all may not be a great idea.What Does an Ultrasound of the Bladder and Kidneys Show?
An ultrasound of the bladder and kidneys can be used to detect various conditions such as kidney stones, infections, cysts, tumors, and more.What Foods Help Repair Kidneys?
If you have chronic kidney disease, it is crucial to track food and fluid intake because diseased kidneys can’t remove waste products from the body like healthy kidneys can. Good foods that help repair your kidneys include apples, blueberries, fish, kale, spinach and sweet potatoes.What Is a Kidney Ureter Bladder X-Ray Study?
A kidney, ureter, and bladder (KUB) X-ray is a diagnostic test that is used for detecting kidney stones and diagnosing multiple disorders of the urinary tract. This diagnostic examination is usually done by injecting contrast media in your veins. The test is usually done on an outpatient basis and you can resume your daily activities as soon as you have finished the scans.What Level of BUN Indicates Kidney Failure?
Blood urea nitrogen (BUN) is one of the parameters measured to ascertain kidney function. BUN indicates the urea nitrogen produced in the body during protein breakdown. There is no definite value of BUN that would diagnose kidney failure.